Police were called at around 2320hrs on Friday, 4 May, to reports of shots fired in Blenheim Grove near to Peckham Rye station.
Officers attended the location and cordons were put in place.
The shutters of a shop in Blenheim Grove were damaged, but there was no reported injury.
Three male suspects rode away from the scene on two mopeds. It is believed that one of the males had fired a shot towards a man who was riding a pedal cycle in Blenheim Grove, but the shot missed and struck the shop.
Trident officers are investigating the incident.
They are appealing for anyone with information, anyone who witnessed the incident or anyone who may have seen the group on two mopeds to call detectives at Trident South via 101, quoting ref 9229/ may4.
To remain anonymous call Crimestoppers on 0800 555 111.